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* This is not a home test kit. You will need to visit a local lab for testing.
Fasting Required: No
Turnaround Time: 2-10 business days
Specimen Type: Blood
Histocompatibility Leukocyte A Antigen, Human Leukocyte A Antigen, Human Lymphocyte Antigen B27
Your white blood cells are important immune system defenders in the fight against germs and disease. But if you have the human leukocyte antigen B27 (HLA B27) on the surface of your white blood cells, that can lead to autoimmune diseases characterized by inflammation and painful joints, including reactive arthritis and ankylosing spondylitis, as well as another condition, anterior uveitis, with inflammation that damages the eyes.
A human leukocyte antigen B27 test determines if you have this antigen in your blood.
If you’re experiencing unexplained joint pain, particularly in the back and neck, then you may need to be tested for HLA B27.
You don’t have to follow any special instructions to prepare for the HLA B27 antigen test.
Test results come back either positive or negative. A positive test confirms that you have the HLA B27 antigen. This may require further investigation, which can include blood, urine, and imaging tests (including x-rays and MRIs). If you need a physician to consult with about a positive HLA B27 test result, we’re here to help you by offering convenient telehealth appointments with one of our board-certified physicians.
We provide easy access to HLA B27 testing. This test is one of more than 400 we offer online, and when it comes time to take it, you can choose from more than 4,000 labs across the country, thanks to our affiliations with leading lab companies Quest Diagnostics and Labcorp.
Here’s just how simple it is to take control of your health with Personalabs:
Step 1: Once you’ve purchased the test you want, download the appropriate lab order. (And you may not even need a doctor’s approval to buy and take the test, depending on the state where you live.)
Step 2: Schedule your blood draw by using our locator tool to pinpoint the lab near you.
Step 3: Complete your blood work at the lab. (Be sure to bring the test order to the lab with you.)
Step 4: Review your results in your secure Personalabs account. The test report typically arrives within 2 to 10 business days after your testing date. (Need the results back by a specific date? Contact us, and we can work with the lab on making that turnaround time happen for you.)
When it comes to healthcare, Personalabs puts the power in your hands. Explore the full range of tests today.
Provider | LabCorp, Quest |
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Order Your Test
Create an account, choose your tests, checkout securely, generate your lab order
Generate & Print Out Lab Order
Our physician network will approve your order within 2-4hrs.
Visit the Lab
The test price decides which lab you will visit: Quest or Labcorp. Find a location in your area.
Get Your Results
Results can be provided in as little as 24-48 hrs. For more complex tests, please contact us for turn around times.
Based on 2,271 reviews subject to moderation
I appreciated the quick turnaround from the time I ordered the laread more
Review of 5/16/2025, reflecting an experience on 5/14/2025 by Patricia S
ALWAYS AN AWESOME JOB
Review of 5/16/2025, reflecting an experience on 5/13/2025 by john P
I use them faithfully. An Excellent service! I great way to manaread more
Review of 5/15/2025, reflecting an experience on 5/12/2025 by Suzanne T
The online test signup was easy, Quest office wait time was minimread more
Review of 5/14/2025, reflecting an experience on 5/11/2025 by Alan W
The reception was very attentive and warm, very fast and professiread more
Review of 5/12/2025, reflecting an experience on 5/9/2025 by Ariel L
Easy to order, quick delivery of order. Prices good whe coupons oread more
Review of 5/12/2025, reflecting an experience on 5/8/2025 by Susan G
makes it easy to manage my health without having to talk to a docread more
Review of 5/10/2025, reflecting an experience on 5/7/2025 by Patrick C
Ordered a test by mistake (no lab order generated) and wasn't fulread more
Review of 5/2/2025, reflecting an experience on 4/14/2025 by Domingo O
Went smoothly
Review of 5/2/2025, reflecting an experience on 4/18/2025 by Stephani R
I live in Massachusetts where most of medical procedures are goveread more
Review of 5/2/2025, reflecting an experience on 4/16/2025 by Helen M
Always quick.
Review of 5/2/2025, reflecting an experience on 4/24/2025 by Joshua T
Easy to find my tests, order, sample, and prompt return of the reread more
Review of 4/19/2025, reflecting an experience on 4/14/2025 by Steven M
Good , but nothing listing what you’re charging for what differenread more
Review of 4/19/2025, reflecting an experience on 4/3/2025 by Rodnet J
The tech was extremely rough with me, physically hurt me and pushread more
Review of 4/19/2025, reflecting an experience on 4/2/2025 by Gretta P
Great service provides easy access to routine wellness and other read more
Review of 4/19/2025, reflecting an experience on 4/10/2025 by Brian B
I appreciated the quick turnaround from the time I ordered the laread more
Review of 5/16/2025, reflecting an experience on 5/14/2025 by Patricia S
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Great service provides easy access to routine wellness and other read more
Review of 4/19/2025, reflecting an experience on 4/10/2025 by Brian B